I am a research associate at IISER Pune who is fascinated by the interactions of mutation, drift, and selection in organismal populations. I am particularly captivated by the complexity that underlies the process of adaptation in seemingly simple asexual systems.
In my current research, I use combinations of bacterial experimental evolution, population genomics, and agent-based simulations to study the following:
The effects of population size on adaptation and fitness trade-offs
The population genetics of divergent character evolution in identical environments
The reasons why costs of adaptation are rarely detected
1. Chavhan, Y., Malusare, S. & Dey, S.
Larger bacterial populations evolve heavier fitness trade-offs and undergo greater ecological specialization.
Heredity 124, 726–736 (2020)
2. Chavhan, Y., Karve, S. & Dey, S.
Adapting in larger numbers can increase the vulnerability of Escherichia coli populations to environmental changes.
Evolution 73, 836–846 (2019)
3. Chavhan, Y., Ali, S. I. & Dey, S.
Larger numbers can impede adaptation in asexual populations despite entailing greater genetic variation.
Evolutionary Biology 46, 1–13 (2019)
4. Karve, S., Daniel, S., Chavhan Y., Anand, A., Kharola, S.S. & Dey, S.
Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity.
Journal of Evolutionary Biology 28, 1131–1143 (2015)
The May 2020 Heredity Podcast featuring my recent work